Episode 1
Up From Ashes
A jailed Murdoch must prove his innocence amid police and government corruption after the constables are ambushed, Ogden is kidnapped, and Brackenreid goes missing.

Detective Murdoch and Dr. Ogden travel to Vancouver Island to visit Murdoch's brother, RCMP officer Jasper Linney. There, they investigate a murder connected to an archaeologist who has uncovered an ancient Indigenous settlement, leading to encounters with the Songhees and Haida nations. Meanwhile, the Brackenreids are offered an investment opportunity that may not be all it seems, and Crabtree and Higgins plan a ski holiday with their sweethearts Nina Bloom and Ruth Newsome that may be more dangerous than expected.
Episode 1
A jailed Murdoch must prove his innocence amid police and government corruption after the constables are ambushed, Ogden is kidnapped, and Brackenreid goes missing.
Episode 2
Murdoch and Watts discover fraud after a wine connoisseur is poisoned.
Episode 3
A recording device made by Alexander Graham Bell assists in the investigation of a murder at a dinner honoring Helen Keller.
Episode 4
Murdoch investigates a surgeon performing cutting-edge organ transplants.
Episode 5
A spate of murders staged as suicides leads Murdoch to suspect a sequential killer targeting the elderly.
Episode 6
In an attempt to solve a murder, Crabtree and Constable Brackenreid go undercover at a boys school.
Episode 7
Murdoch investigates a car accident and uncovers sinister motives.
Episode 8
Brackenreid begins painting again and gets the attention of a wealthy patron while investigating an artist's murder.
Episode 9
After obituaries are published in advance of two men's deaths, Murdoch discovers more intended victims with a member of Station House Number Four among them. He must keep them alive before their predicted demise.
Episode 10
Murdoch investigates a death which may have been caused by a high-speed travel device.
Episode 11
Murdoch and Brackenreid find some unsportsmanlike behaviour while investigating the violent death of a cricket player on the pitch.
Episode 12
Murdoch investigates when a statue of the Virgin Mary gifted to his church begins miraculously weeping.
Episode 13
When the judge of a cooking contest is poisoned, Murdoch realizes that other competitors also tasted the tainted ingredient, including Crabtree and Margaret Brackenreid.
Episode 14
When Theodore Roosevelt sneaks into Canada for a hunting trip, Murdoch discovers the American President is the quarry.
Episode 15
As Murdoch investigates a murder with connections to vaudeville entertainers Harry and Al Jolson, Watts unravels a mystery about his own family.
Episode 16
Crabtree goes undercover at a chess tournament to investigate the murder of a Russian master.
Episode 17
Murdoch and Ogden put aside a personal matter when Nate Desmond is charged with murder.
Episode 18
Season Finale - An argument leads Murdoch to help a man looking for his missing wife, Crabtree contemplates his future with Nina and the Station House team works on a grisly murder.